by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free

free read Lithium: A Doctor, a Drug, and a Breakthrough

Lithium: A Doctor, a Drug, and a Breakthrough

review Lithium: A Doctor, a Drug, and a Breakthrough × eBook or Kindle ePUB Enefit from prestigious research training or big funding sources Cades laboratory was the unused pantry of an isolated mental hospital As Brown shows however these humble conditions were the secret to his historic success Cade was free to follow his own restless curiosity rather than answer to an external funding source As Lithium makes tragically clear medical researchat least in Americahas transformed in such a way that serendipitous discoveries like Cades are unlikely to occur ever againRecently described by the New York Times as the Cinderella of psychiatric drugs lithium has saved countless of lives and billions of dollars in healthcare costs In this revelatory biography of a drug and the man who fought for its discovery Brown crafts a captivating picture of modern medical historyrevealing just how close we came to passing over this extraordinary cur. My dad is a psychiatrist with a pharmacy degree Loved this book So glad I purchased for his 80th birthday

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review Lithium: A Doctor, a Drug, and a Breakthrough × eBook or Kindle ePUB The remarkable untold story of a miracle drug the forgotten pioneer who discovered it and the fight to bring lithium to the massesThe DNA double helix penicillin the X ray insulinthese are routinely cited as some of the most important medical discoveries of the twentieth century And yet the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most importantyet largely unsungbreakthroughs of the modern era In Lithium Walter Brown a practicing psychiatrist and professor at Brown reveals two unlikely success stories that of John Cade the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution and that of a miraculous metal rescued from decades of stigmatizationFrom insulin comas and lobotomy to incarceration to exile Brown chronicles the troubling history of the diagnosis and of. This is a fascinating story of how lithium a simple element became a modern treatment for a disabling psychiatric disorder which is characterized without drama and with empathy Along the way it chronicles the foibles of 19th century pseudoscience the difficulties professionals face in giving up old ideas and practices the personal development of scientific imagination and the challenges of translating clinical discovery into practice Particularly insightful is the distinction between systematic scientists and artistic scientists the former operating by rules the latter by intuition The reader will develop an appreciation of how the scientific method is sometimes a retroactive fiction that conveniently overlooks the role of chance precedent unplanned observation unexpected collaboration and the human elements involved in investigation This is a great read for those interested in clinical discovery bipolar disease translational medicine and the philosophy of science THE SECRET COMMONWEALTH: THE BOOK OF DUST VOLUME TWO (202 JEUNESSE) remarkable untold story of a miracle drug the forgotten pioneer who discovered it and the fight to bring lithium to the massesThe DNA double helix penicillin the X How to Make an Apple Pie and See the World (Dragonfly Books) ray insulinthese are Le Mystère du train de la nuit (French Edition) routinely cited as some of the most important medical discoveries of the twentieth century And yet the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most importantyet largely unsungbreakthroughs of the modern era In Lithium Walter Brown a practicing psychiatrist and professor at Brown Alice au pays des merveilles (Folio Junior Textes classiques) (French Edition) reveals two unlikely success stories that of John Cade the physician whose discovery would come to save an untold number of lives and launch a pharmacological Briséïs: Tome 3, Ombres et chimères - Partie 2 (Saga Fantastique) (French Edition) revolution and that of a miraculous metal Interdit !: Roman pour enfants (8 ans et) (DEUZIO t. 27) rescued from decades of stigmatizationFrom insulin comas and lobotomy to incarceration to exile Brown chronicles the troubling history of the diagnosis and of. This is a fascinating story of how lithium a simple element became a modern treatment for a disabling psychiatric disorder which is characterized without drama and with empathy Along the way it chronicles the foibles of 19th century pseudoscience the difficulties professionals face in giving up old ideas and practices the personal development of scientific imagination and the challenges of translating clinical discovery into practice Particularly insightful is the distinction between systematic scientists and artistic scientists the former operating by La Belle Sauvage: The Book of Dust Volume One (182 JEUNESSE) rules the latter by intuition The Hollowpox: The Hunt for Morrigan Crow Book 3 (Nevermoor) reader will develop an appreciation of how the scientific method is sometimes a Harry Potter and the Philosopher's Stone retroactive fiction that conveniently overlooks the The Case of the Missing Marquess: An Enola Holmes Mystery role of chance precedent unplanned observation unexpected collaboration and the human elements involved in investigation This is a great Les Contes de Beedle le Barde read for those interested in clinical discovery bipolar disease translational medicine and the philosophy of science

Walter A. Brown ê 3 read & download

review Lithium: A Doctor, a Drug, and a Breakthrough × eBook or Kindle ePUB Ten ineffective treatment of bipolar disorder through the centuries before the publication of a groundbreaking research paper in 1949 Cades Lithium Salts in the Treatment of Psychotic Excitement described for the first time lithiums astonishing efficacy at both treating and preventing the recurrence of manic depressive episodes and would eventually transform the lives of patients pharmaceutical researchers and practicing physicians worldwide And yet as Brown shows it would be decades before lithium would overcome widespread stigmatization as a dangerous substance and the resistance from the pharmaceutical industry which had little incentive to promote a naturally occurring drug that could not be patentedWith a vivid portrait of the storys unlikely hero John Cade Brown also describes a devoted naturalist who unlike many modern medical researchers did not b. Lithium is a drug also used in batteries but the drug lithium has had significant impact on the field of bipolar disorders The book by Brown Lithium is a wonderful history of the discovery of lithium as a therapeutic for manic depression the earlier name for bi polar disorders Cade the investigator who established its efficacy and effectiveness was an example of the lone researcher no funding and using himself as the Phase I test subject to determine if it were even safeI first saw bi polar disorder in the mid 1950s in a relative The patient would swing from a normal state to a depressed state sometimes exacerbated by alcohol then rapidly swing to a manic state The manic state would involve extremes of behavior avoiding any base in reality often attempts at life changing actions totally inconsistent with the patient s capabilities For example the patient would suddenly want to enter the wholesale fish business then buy a truck fill it with fish and then collapse into a depressive state Needless to say the fish were left unattendedIn those days the remedies were limited There was Bellevue Hospital in New York a short term critical care facility and then the city mental hospital on Ward s Island Some patients underwent shock therapy but for many it was just a wait and see Extreme manic states could be medicated and then electro convulsedI saw several other patients during that period thanks to my grandmother s friend from Medical School days Dr Louise Despert a prominent New York psychiatrist She dealt with many children and this was often a significant ailment It was not till the late 1960s that in visits to McLean Hospital a Harvard affiliate in Belmont MA that I saw the large number of bipolar patients but by this time various medications were becoming available lithium amongst them From 1968 to 1978 the patients in Massachusetts psychiatric facilities went from some 20000 to less than 2000 due mainly to the increase in various therapeutics Many bi polar patients could now live a normal as best as possible lifeLithium was one of the key therapeutics used Brown thus details this tale of Cade returning from WW II working at an Australian psychiatric hospital and personally and individually exploring the use of lithium in a salt form Cade eventually writes this up and slowly gets some notice not so much in the 1950s but so in the 1960s It is a tale of a researcher focused on a specific disorder with a target medication then facing the world of the professional researchers some believers and many deniers Brown does a superb task in relating the times and the nature of others looking into this disorder those accepting and those rejecting Much of what Cade did was before the time of well structured clinical trials and his approach would not even be allowed in today s world but Brown shows how uickly Cade was able to demonstrate effectiveness and efficacy albeit limitedBrown then continues with the acceptance by the psychiatric community of lithium and how it made life much acceptable to those with bi polar disorder Overall this is a wonderful book showing the dedication and brilliance of Cade and then showing the complexity of getting a new approach accepted by a complex medical community This is a superb book and worthy of a readMy only criticism and this is uite limited is that a better understanding of the bi polar patients and their plights For almost all they have no control of their often extreme and bizarre behavior Also as with many therapeutics pharmaceuticals the side effects can be uite severe and limits the drug s effectiveness Most people have limited exposure to bi polar disorders but they are common than one thinks and this book sheds light on these facts


5 thoughts on “by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free

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    by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free This is a fascinating story of how lithium a simple element became a modern treatment for a disabling psychiatric disorder which is characterized without drama and with empathy Along the way it chronicles the foibles of 19th century pseudoscience the difficulties professionals face in giving up old ideas and practices the personal development of scientific imagination and the challenges of translating clinical discove

  2. says: free download ó eBook or Kindle ePUB ê Walter A. Brown by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free

    by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free Lithium is a drug also used in batteries but the drug lithium has had significant impact on the field of bipolar disorders The book by Brown Li

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    free read Lithium: A Doctor, a Drug, and a Breakthrough by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free My dad is a psychiatrist with a pharmacy degree Loved this book So glad I purchased for his 80th birthday

  4. says: by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free

    by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free free download ó eBook or Kindle ePUB ê Walter A. Brown A fascinating and important story Well written

  5. says: free download ó eBook or Kindle ePUB ê Walter A. Brown by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free Walter A. Brown ê 3 read & download

    by Walter A. Brown : Lithium: A Doctor, a Drug, and a Breakthrough – Pdf/Epub Free Informative about Lithium as a treatment and how it was discovered but also very ranty

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  • Lithium: A Doctor, a Drug, and a Breakthrough
  • Walter A. Brown
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  • 03 October 2019
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